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Quarterly since 2025
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Asia Pacific Academy of Science Pte. Ltd. (APACSCI) specializes in international journal publishing. APACSCI adopts the open access publishing model and provides an important communication bridge for academic groups whose interest fields include engineering, technology, medicine, computer, mathematics, agriculture and forestry, and environment.
Volume Arrangement
2025
Featured Articles
Psoriasis is a common, chronic, and inflammatory skin disease. Macrophages account for about 61.3% of the inflammatory cells infiltrating psoriatic lesions. Modulating macrophage polarization, inhibiting their infiltration, and targeting the secretion of inflammatory factors and associated inflammatory pathways by these cells can alleviate psoriasis symptoms and inflammation. Moreover, nanomaterials as novel drug carriers, offer unique advantages such as large surface area, easy modification, high biocompatibility, good biodegradability, enhanced systemic adsorption, etc. Nanomaterials have great potential for efficient drug delivery and release, as well as improving therapeutic efficacy while reducing adverse effects. By systematically addressing the role of macrophages in psoriasis pathogenesis and the potential of nanomaterials in treating psoriasis through modulating macrophages, this review enhances our understanding of the disease mechanism and holds promise for novel therapeutic breakthroughs and advancements in the future treatment of psoriasis.
| Issue | Title | |
| Vol 39, No 2 (2025) | Liquiritigenin attenuates myocardial ischemia-reperfusion injury by activating the Nrf2/HO-1 pathway | Abstract PDF |
| Huiyu Jia, Ting Wang, Min Si, Zheng Ma, Shengyong Luo | ||
| Vol 39, No 2 (2025) | Amelioration of COVID-19 comorbid depressions via interleukin 6 with agomelatine | Abstract PDF |
| Yang I. Cao | ||
| Vol 39, No 2 (2025) | Macrophages in the pathogenesis of psoriasis and anti-psoriatic nanotherapies | Abstract PDF |
| Mingmin Ni, Kaitao Wang, Yongqing Tian, Lifu Zhou, Xiaohua Yang, Mingmin Ni | ||
| Vol 39, No 2 (2025) | An efficient optimized deep learning model for diabetic retinopathy classification | Abstract PDF |
| Mary Vespa Mathiazhagan, Agees Kumar Chellappan | ||
| Vol 39, No 2 (2025) | Causal relationships between cathepsins and autoimmune diseases: A mendelian randomization study | Abstract PDF |
| Yan Xia, Dan Shan, Ke Yi | ||
| Vol 39, No 2 (2025) | A review of glycolysis and autism spectrum disorder: The dual role of lactic acid in neurodevelopment and function | Abstract PDF |
| Ziqing Jiang, Yingxin Zhou, Peiqun Liu, Yiying Zhou, Yuxuan Gao, Qin Fan, Jintao Lin | ||
| Vol 39, No 2 (2025) | Integrating comprehensive mental health support proposal for well-being | Abstract PDF |
| Chafaa Hamrouni | ||
| Vol 39, No 2 (2025) | Integration of clinical data with results from next-generation sequencing technology used to detect somatic and germline variants in patients with high-grade serous ovarian cancer | Abstract PDF |
| Patrycja Aleksandra Bukłaho, Joanna Kiśluk, Witold Bauer, Jacek Nikliński | ||
| Vol 39, No 2 (2025) | Investigating epigenetic changes in the DARP gene as a potential predictive biomarker in ovarian cancer: A pyrosequencing analysis of FFPE samples | Abstract PDF |
| Akbar Ibrahimov, Fidan Novruzova | ||
| Vol 39, No 2 (2025) | About therapeutic action of silver ions: A brief overview | Abstract PDF |
| Anna A. Antsiferova, Pavel K. Kashkarov | ||
| Vol 39, No 1 (2025) | Celastrus orbiculatus Extract Inhibits the Malignancy ofNon-Small Cell Lung Cancer Cells ThroughPI3K/AKT/mTOR Pathway | Abstract PDF |
| Xuejiao Yang, Dongdong Zhang, Yan Wei, Yulan Zheng | ||
| Vol 39, No 1 (2025) | Interaction between miR-140 and HDAC4 in GastricCancer Metastasis | Abstract PDF |
| Yiwei Zhang, Shaoqing Wang, Feng Gao, Xiaoying Wang, Yurong Sun, Xianyan Wang | ||
| Vol 39, No 1 (2025) | Pathogenic Detection of Alveolar Lavage Fluid inChildren with Lobar Pneumonia | Abstract PDF |
| Zhiping Li, Yuxia Liu | ||
| Vol 39, No 1 (2025) | Luteolin Reduces Temozolomide Resistance viaRegulating PI3K/AKT Pathway in Glioma | Abstract PDF |
| Ran Luo, Yanting Liu, Wei Gong, Jian Chen, Chunlei Tian | ||
| Vol 39, No 1 (2025) | Effects of Histone Deacetylase 2 onEpithelial-Mesenchymal Transition in PulmonaryFibrosis | Abstract PDF |
| Yu Liu, Songjun Shao, Yu Tan, Shanyu Wang, Peng Zheng, Jing Han, Ying Zhao, Shanshan Rao | ||
| Vol 39, No 1 (2025) | KDM6B Promotes the Development, Progression andMetastasis of Oesophageal Cancer throughDemethylation of Histones in the LDHA PromoterRegion | Abstract PDF |
| Cai-Lin Zhu, Wei-Yun Bi, Hong-Tao Li, Zhi-Yong Zhang | ||
| Vol 39, No 1 (2025) | Obesity Factors in Failure Analysis of Cemented TotalHip Replacement | Abstract PDF |
| Lanfeng Zhang, Hongtao Liu, Feng Yuan, Tianchi Chen, Lin Xu, Jingmao Wang, Yancheng Wang, Ziyue Tong | ||
| Vol 39, No 1 (2025) | Identification of PROZ as a Cancer-related Gene inHepatocellular Carcinoma under Hypoxia Condition | Abstract PDF |
| Xueli Yang, Miao Liu, Tao Deng | ||
| Vol 39, No 1 (2025) | Rhamnazin Inhibits Malignant Progression of ProstateCancer Cells via DPP4/JAK/STAT Signaling Pathway | Abstract PDF |
| Shouyu Xue, Aimin Geng, Ting Lian | ||
| Vol 39, No 1 (2025) | Causal Role of Immune Cells in Gastric Cancer: AMendelian Randomisation (MR) Study | Abstract PDF |
| Peng Gao, Qiangxin Zheng, Junqing Gan, Jie Song, Wenting Jia, Jilong Yang | ||
| Vol 39, No 1 (2025) | A Meta-Analysis of the Impact of Proton Pump Inhibitors on Survival Outcomes in NSCLC Treated with Immunotherapy | Abstract PDF |
| Lina Sheng, Xiaofei Li | ||
| Vol 39, No 1 (2025) | LINC00174 Accelerates the Progression of Non-Small Cell Lung Cancer via Modulating EP300/NFAT5 Axis | Abstract PDF |
| Xiaogang Peng, Chao Zhang, Guangming Xiang, Zheng Gong, Gengyun Sun | ||
| Vol 39, No 1 (2025) | LncRNA MATN1-AS1/miR-200c-3p/HAS-2 AxisModulates Proliferation, Invasiveness, Migration andEpithelial-Mesenchymal Transition of Colorectal CancerCells | Abstract PDF |
| Dengke Fu, Yang Chen, Dongkui Xu | ||
| Vol 39, No 1 (2025) | HO-1 Prevents Oxidative Stress Damage, PromotesProliferation and Inhibits Apoptosis of OsteoblastsInduced by H2O2 | Abstract PDF |
| Maimaiti Xiayimaierdan, Jinyong Huang, Chenchen Fan, Feiyu Cai, Zengru Xie | ||
| Vol 39, No 1 (2025) | The Transcription Factor ELK1 Promotes EsophagealSquamous Cell Carcinoma Progression by Activating theCDK4/Wnt/β-catenin Pathway | Abstract PDF |
| Na Zhan, Liping Zou, Qin Du | ||
| 1 - 25 of 25 Items | ||
Editor-in-Chief
Medical Genetics, University of Torino Medical School, Italy
Co-Editor-in-Chief
Department of Biomedical, Surgical and Dental Sciences, University of Milan, Italy
Indexing & Archiving
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Scopus (CiteScore: 2.2)
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News & Announcements
2025-02-01
In addition to the first issue that has already been published by the original publisher, there will be four more issues released this year, with scheduled publication dates in March, June, September, and December respectively.
2025-01-21
Starting from Volume 39 Issue 2 (2025), the ownership of Journal of Biological Regulators and Homeostatic Agents (ISSN: 0393-974X (P); 1724-6083 (O)) will be transferred from Biolife Sas to Asia Pacific Academy of Science Pte. Ltd. As of 21 January 2025, authors should make submissions to the new journal system and follow the author guidelines. Asia Pacific Academy of Science Pte. Ltd. will take over the publication of manuscripts being processed.