Focus on the cariogenic process: microbial and biochemical interactions with teeth and oral environment

G Dipalma, AD Inchingolo, F Inchingolo, IA Charitos, M Di Cosola, AP Cazzolla

Article ID: 3942
Vol 35, Issue 2, 2021
DOI: https://doi.org/10.23812/20-747-A
Received: 9 May 2021; Accepted: 9 May 2021; Available online: 9 May 2021; Issue release: 9 May 2021

Abstract

This paper aims to describe the biochemical interactions between teeth and the oral environment that occur during the caries process, hence it covers all the steps related to physico-chemical reactions, including the most up-to-date theoretical basis in the clinical application for the prevention and treatment of caries. The terms ‘demineralization’ and ‘remineralization’ that characterise this process were analysed, as well as the role of the microbiota in its interaction with the hard surface of the teeth. The biochemical mechanisms that lead to the onset of carious lesions and those that occur during the healing and repair of such lesions are listed.


Keywords

dental caries;dental diseases;microbiology;microbiota;oral biochemistry;saliva


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