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Focus on the cariogenic process: microbial and biochemical interactions with teeth and oral environment
Vol 35, Issue 2, 2021
Abstract
This paper aims to describe the biochemical interactions between teeth and the oral environment that occur during the caries process, hence it covers all the steps related to physico-chemical reactions, including the most up-to-date theoretical basis in the clinical application for the prevention and treatment of caries. The terms ‘demineralization’ and ‘remineralization’ that characterise this process were analysed, as well as the role of the microbiota in its interaction with the hard surface of the teeth. The biochemical mechanisms that lead to the onset of carious lesions and those that occur during the healing and repair of such lesions are listed.
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Copyright (c) 2021 G Dipalma, AD Inchingolo, F Inchingolo, IA Charitos, M Di Cosola, AP Cazzolla
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Medical Genetics, University of Torino Medical School, Italy

Department of Biomedical, Surgical and Dental Sciences, University of Milan, Italy