
Enhancing cancer diagnosis accuracy with a hybrid ML model: A study on UAE patient data
Vol 3, Issue 2, 2025
Download PDF
Abstract
Preliminary identification of cancer is still essential because it can greatly improve the chances of survival of a patient, as cancer is the leading reason of death internationally. In this study, we introduce a mixed machine learning (ML) model using support vector machines (SVM) and random forest (RF) algorithms. To improve accuracy in diagnosing cancer, classifiers such as linear regression (LinReg), support vector machines (SVM), and logistic regression (LogReg) are used. This way, the model is tested and validated using the UAE Cancer. It contains medical records of all patients, their demographic information, clinical information, and outcomes. Our results demonstrate that the hybrid model achieved 98.3% accuracy, 98.5% recall, and 0.99 AUC-ROC, outperforming individual classifiers. Policies are justiciable despite the difficulties of needing to validate findings from many datasets, make them easy to use clinically, and manage biases in the available information. Because of this study, people are considering how hybrid ML models can be beneficial in clinical care and are encouraging more research on cancer diagnostics.
Keywords
References
1. Hossain MS, Basak N, Mollah MA, et al. Ensemble-based multiclass lung cancer classification using hybrid CNN-SVD feature extraction and selection method. PLoS One. 2025; 20(3): e0318219. doi: 10.1371/journal.pone.0318219
2. Al-Jamimi HA, Ayad S, El Kheir A. Integrating Advanced Techniques: RFE-SVM Feature Engineering and Nelder-Mead Optimized XGBoost for Accurate Lung Cancer Prediction. IEEE Access. 2025. doi: 10.1109/ACCESS.2025.3536034
3. Raigonda MR, Mama G, Bainoor R. Lung cancer detection using machine learning techniques. International Journal of Educational Research. 2025; 128: 135.
4. Abe A, Nyathi M, Okunade A. Lung cancer diagnosis from computed tomography scans using convolutional neural network architecture with Mavage pooling technique. AIMS Medical Science. 2025; 12(1): 13-27. doi: 10.3934/medsci.2025002
5. Naemi A, Tashk A, Sorayaie Azar A, et al. Applications of Artificial Intelligence for Metastatic Gastrointestinal Cancer: A Systematic Literature Review. Cancers. 2025; 17(3): 558. doi: 10.3390/cancers17030558
6. Suvanasuthi R, Therasakvichya S, Kanchanapiboon P, et al. Analysis of precancerous lesion-related microRNAs for early diagnosis of cervical cancer in the Thai population. Scientific reports. 2025; 15(1): 142. doi: 10.1038/s41598-024-84080-1
7. Peng X, Bian H, Zhao H, et al. Research hotspots and trends in lung cancer STAS: a bibliometric and visualization analysis. Frontiers in Oncology. 2025; 14: 1495911. doi: 10.3389/fonc.2024.1495911
8. Alzahrani A. Early Detection of Lung Cancer Using Predictive Modeling Incorporating CTGAN Features and Tree-Based Learning. IEEE Access. 2025. doi: 10.1109/ACCESS.2025.3543215
9. Javanmard Z, Shahraki SZ, Safari K, et al. Artificial intelligence in breast cancer survival prediction: a comprehensive systematic review and meta-analysis. Frontiers in Oncology. 2025; 14: 1420328. doi: 10.3389/fonc.2024.1420328
10. Abdullah KA, Marziali S, Nanaa M, et al. Deep learning-based breast cancer diagnosis in breast MRI: systematic review and meta-analysis. European Radiology. 2025. doi: 10.1007/s00330-025-11406-6
11. Jiang X, Hu Z, Wang S, et al. Deep learning for medical image-based cancer diagnosis. Cancers. 2023; 15(14): 3608. doi: 10.3390/cancers15143608
12. Afifi S, Faragallah MH, Taha R, et al. The Role of Artificial Intelligence in Improving Histopathological Diagnosis of Prostate Cancer: A Review. Journal of Engineering and Science in Medical Diagnostics and Therapy. 2025; 8(2): 020801. doi: 10.1115/1.4067302
13. Jee JJ, Lim J, Park S, et al. Gut microbial community differentially characterizes patients with nonalcoholic fatty liver disease. Journal of Gastroenterology and Hepatology. 2022; 37(9): 1822-1832. doi: 10.1111/jgh.15903
14. Jassam IF, Mukhlif AA, Nafea AA, et al. A review of breast cancer histological image classification: Challenges and limitations. Iraqi Journal for Computer Science and Mathematics. 2025; 6(1): 1. doi: 10.52866/2788-7421.1232
15. Patel S, Yadav D, Kumar D. Integrating machine learning to customize chemotherapy for oral cancer patients. Oral Oncology Reports. 2025; 13: 100711. doi: 10.1016/j.oor.2024.100711
16. Hassan BAR, Mohammed AH, Hallit S, et al. Exploring the role of artificial intelligence in chemotherapy development, cancer diagnosis, and treatment: present achievements and future outlook. Frontiers in Oncology. 2025; 15: 1475893. doi: 10.3389/fonc.2025.1475893
17. Gani MO, Kethireddy S, Adib R, et al. Structural causal model with expert augmented knowledge to estimate the effect of oxygen therapy on mortality in the icu. Artificial intelligence in medicine. 2023; 137: 102493. doi: 10.1016/j.artmed.2023.102493
18. Olawade DB, Clement David-Olawade A, Adereni T, et al. Integrating AI into cancer immunotherapy—A narrative review of current applications and future directions. Diseases. 2025; 13(1): 24. doi: 10.3390/diseases13010024
19. Han W, Wang T, He Z, et al. Global research trends on gastrointestinal cancer and mental health (2004–2024): a bibliographic study. Frontiers in Medicine. 2025; 12: 1515853. doi: 10.3389/fmed.2025.1515853
20. Padilla CS, Bergerot CD, Dijke K, et al. Health-Related quality of life (HRQoL) assessments in research on patients with adult rare solid cancers: A State-of-the-Art review. Cancers. 2025; 17(3): 387. doi: 10.3390/cancers17030387
21. Hu Z, Luo M, He R, et al. Development and validation of a risk prediction model for PICC-related venous thrombosis in patients with cancer: a prospective cohort study. Scientific Reports. 2025; 15(1): 4654. doi: 10.1038/s41598-025-89260-1
22. Murthy NN, Thippeswamy K. Fuzzy-ER Net: Fuzzy-based efficient residual network-based lung cancer classification. Computers and Electrical Engineering. 2025; 121: 109891. doi: 10.1016/j.compeleceng.2024.109891
23. Hou D, Zhou H, Tang Y, et al. Dynamic visualization of Computer-Aided peptide design for Cancer therapeutics. Drug Design, Development and Therapy. 2025. 1043-1065. doi: 10.2147/DDDT.S497126
24. Mishan MA, Choo YM, Winkler J, et al. Manzamine A: A promising marine-derived cancer therapeutic for multi-targeted interactions with E2F8, SIX1, AR, GSK-3β, and V-ATPase-A systematic review. European Journal of Pharmacology. 2025. 177295. doi: 10.1016/j.ejphar.2025.177295
25. Weickert MO. Factors influencing costs of cancer care for patients with neuroendocrine neoplasms. Neuroendocrinology. 2025. doi: 10.1159/000544050
26. Dolton G, Thomas H, Tan LR, et al. MHC-related protein 1–restricted recognition of cancer via a semi-invariant TCR-α chain. The Journal of Clinical Investigation. 2025; 135(1). doi: 10.1172/JCI181895
27. Zhu C, Yang J, Liu L, et al. Bibliometric analysis of glycolysis and prostate cancer research from 2004 to 2024. Discover Oncology. 2025; 16(1): 34. doi: 10.1007/s12672-025-01790-2
28. Baxevanis CN, Goulielmaki M, Tsitsilonis OE, et al. Onco: Covering the Field of Cancer Research and Cancer Therapies in 2024. Onco. 2025; 5(1): 5. doi: 10.3390/onco5010005
29. Islam MA, Yeasmin S, Hosen A, et al. Harnessing predictive analytics: The role of machine learning in early disease detection and healthcare optimization. Journal of Ecohumanism. 2025; 4(3): 312-321. doi: 10.62754/joe.v4i3.6642
30. Tan SL, Selvachandran G, Paramesran R, et al. Lung cancer detection systems applied to medical images: a state-of-the-art survey. Archives of Computational Methods in Engineering. 2025; 32(1): 343-380. doi: 10.1007/s11831-024-10141-3
31. Singh A, Kumar R, Patel S, et al. The role of artificial intelligence in personalized cancer therapy. Cancer Treatment Reviews. 2025; 117: 102521. doi: 10.1016/j.ctrv.2025.102521
32. Đorđević AC, Karalis V. Artificial intelligence in drug development, clinical trials, and healthcare. Acta medica Medianae. 2025; 64(1).
Supporting Agencies
Copyright (c) 2025 Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License.

Prof. Maode Ma
Qatar University, Qatar
The field of computer and telecommunications engineering is rapidly advancing, with the following being some of the latest developments.
more
We are pleased to congratulate the first anniversiry of the journal of Computer and Telecommunication Engineering (CTE).
more
Owing to the tireless dedication of the editor-in-chief, editorial board members, and the in-house editorial team, we are proud to announce the successful online launch of the first issue of Computer and Telecommunication Engineering.
Asia Pacific Academy of Science Pte. Ltd. (APACSCI) specializes in international journal publishing. APACSCI adopts the open access publishing model and provides an important communication bridge for academic groups whose interest fields include engineering, technology, medicine, computer, mathematics, agriculture and forestry, and environment.

.jpg)

.jpg)
