Quantum Dots as Functional Nanosystems for Enhanced Biomedical Applications

Pronama Biswas, Asmita Saha, Bhoomika Sridhar, Anwesha Patel, Belaguppa Manjunath Ashwin

Article ID: 7876
Vol 38, Issue 3, 2024
DOI: https://doi.org/10.23812/j.biol.regul.homeost.agents.20243803.145
Received: 20 March 2024; Accepted: 20 March 2024; Available online: 20 March 2024; Issue release: 20 March 2024

Abstract

Quantum Dots (QDs) have emerged as promising nanomaterials with unique optical and physical properties, making them highly attractive for various applications in biomedicine. This review provides a comprehensive overview of the types, modes of synthesis, characterization, applications, and recent advances of QDs in the field of biomedicine, with a primary focus on bioimaging, drug delivery, and biosensors. The unique properties of QDs, such as tunable emission spectra, long-term photostability, high quantum yield, and targeted drug delivery, hold tremendous promise for advancing diagnostics, therapeutics, and imaging techniques in biomedical research. However, several significant hurdles remain before their full potential in the biomedical field, like bioaccumulation, toxicity, and short-term stability. Addressing these hurdles is essential to effectively incorporate QDs into clinical use and enhance their influence on healthcare outcomes. Furthermore, the review conducts a critical analysis of potential QD toxicity and explores recent progress in strategies and methods to mitigate these adverse effects, such as surface modification, surface coatings, and encapsulation. By thoroughly examining current research and recent advancements, this comprehensive review offers invaluable insights into both the future possibilities and the challenges that lie ahead in fully harnessing the potential of QDs in the field of biomedicine, promising a revolution in the landscape of medical diagnostics, therapies, and imaging technologies.


Keywords

Quantum Dots;bioimaging;drug delivery;biosensors;toxicity


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