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From Gut to Womb: Linkage of Gut Microbiome with Sex Hormones And Fertility
Vol 37, Issue 10, 2023
Abstract
The gut microbiota (GM) plays a significant role in regulating the immune system, digestion, and estrogen levels. However, the extent of its impact on pregnancy and abortion remains unclear. Recent studies have demonstrated the importance of the gut-brain axis in digestion and psychological communication between the brain and gut tract. That suggests that GM may also play a role in fertility, as it can influence the brain and immune system. Herein, we aim to determine the evidential relationship between the gut microbiome and fertility in females. Moreover, we also discuss the potential mechanisms by which the GM can affect pregnancy and abortion.
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Copyright (c) 2023 Ali Afzal, Maryam Riasat, Muddasir Hassan Abbasi, Hamid Nawaz, Nadeem Sheikh, Muhammad Ahsan Ashraf, Nimra Afzal, Muhammad Babar Khawar
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Medical Genetics, University of Torino Medical School, Italy
Department of Biomedical, Surgical and Dental Sciences, University of Milan, Italy