Topical toluidine blue-mediated photodynamic therapy for the treatment of oral lichen planus

A. Romano, M. Contaldo, F. Della Vella, D. Russo, C. Lajolo, R. Serpico, D. Di Stasio

Article ID: 6779
Vol 33, Issue 3S1, 2019
DOI: https://doi.org/10.54517/jbrha6779
Received: 9 July 2019; Accepted: 9 July 2019; Available online: 9 July 2019; Issue release: 9 July 2019

Abstract

Photodynamic Therapy (PDT) is a minimally invasive approach that has shown promising results in management of oral, head and neck lesions. PDT can be used alone or in combination with other conventional treatments (surgery, chemotherapy, radiotherapy). Oral Lichen Planus (OLP) is a mucosal and cutaneous chronic disease characterized by an autoimmune insult of basal keratinocytes. We aim to evaluate the feasibility of topical toluidine blue-mediated PDT for the treatment of oral cavity multifocal homogeneous white lesions by oral lichen planus without dysplastic features.


Keywords

photodynamic therapy;toluidine blue;oral lichen planus


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