TOOTH AGENESIS: PART 1. INCIDENCE AND DIAGNOSIS IN ORTHODONTICS

D. DE SANTIS; P. PANCERA; S. SINIGAGLIA; P. FACCIONI; D. BERTOSSI; U. LUCIANO; F. ZOTTI; M. MATARESE; A. LUCCHESE; S. CROCE; M. MANUELLI; D. DONADELLO; G. RICCIARDI; N. KUMAR; R. NOCINI; M. ALBANESE

doi:10.54517/jbrha6758

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Macrophages in the pathogenesis of psoriasis and anti-psoriatic nanotherapies

Psoriasis is a common, chronic, and inflammatory skin disease. Macrophages account for about 61.3% of the inflammatory cells infiltrating psoriatic lesions. Modulating macrophage polarization, inhibiting their infiltration, and targeting the secretion of inflammatory factors and associated inflammatory pathways by these cells can alleviate psoriasis symptoms and inflammation. Moreover, nanomaterials as novel drug carriers, offer unique advantages such as large surface area, easy modification, high biocompatibility, good biodegradability, enhanced systemic adsorption, etc. Nanomaterials have great potential for efficient drug delivery and release, as well as improving therapeutic efficacy while reducing adverse effects. By systematically addressing the role of macrophages in psoriasis pathogenesis and the potential of nanomaterials in treating psoriasis through modulating macrophages, this review enhances our understanding of the disease mechanism and holds promise for novel therapeutic breakthroughs and advancements in the future treatment of psoriasis.

TOOTH AGENESIS: PART 1. INCIDENCE AND DIAGNOSIS IN ORTHODONTICS

D. DE SANTIS, P. PANCERA, S. SINIGAGLIA, P. FACCIONI, D. BERTOSSI, U. LUCIANO, F. ZOTTI, M. MATARESE, A. LUCCHESE, S. CROCE, M. MANUELLI, D. DONADELLO, G. RICCIARDI, N. KUMAR, R. NOCINI, M. ALBANESE

Article ID: 6758
Vol 33, Issue 1S1, 2019

DOI: https://doi.org/10.54517/jbrha6758

Received: 11 March 2019; Accepted: 11 March 2019; Available online: 11 March 2019; Issue release: 11 March 2019

Abstract

Dental agenesis has a great clinical significance due to its frequency during daily practice and thetherapeutic problems that can arise from it. This paper will explore the incidence of dental agenesis, itsdiagnosis and how this anomaly affects the teeth differently. The second subsequent paper will look atits treatment and management.

Keywords

tooth agenesis;dental agenesis;hypodontia;oligodontia;orthodontics;diagnosis

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Copyright (c) 2019 D. DE SANTIS, P. PANCERA, S. SINIGAGLIA, P. FACCIONI, D. BERTOSSI, U. LUCIANO, F. ZOTTI, M. MATARESE, A. LUCCHESE, S. CROCE, M. MANUELLI, D. DONADELLO, G. RICCIARDI, N. KUMAR, R. NOCINI, M. ALBANESE

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Medical Genetics, University of Torino Medical School, Italy

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Department of Biomedical, Surgical and Dental Sciences, University of Milan, Italy

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2025-02-01

Notice of Change in Publication Schedule

In addition to the first issue that has already been published by the original publisher, there will be four more issues released this year, with scheduled publication dates in March, June, September, and December respectively.

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Starting from Volume 39 Issue 2 (2025), the ownership of Journal of Biological Regulators and Homeostatic Agents (ISSN: 0393-974X (P); 1724-6083 (O)) will be transferred from Biolife Sas to Asia Pacific Academy of Science Pte. Ltd. As of 21 January 2025, authors should make submissions to the new journal system and follow the author guidelines. Asia Pacific Academy of Science Pte. Ltd. will take over the publication of manuscripts being processed.

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