Treatment options of simple bone cysts: the role of bone substitutes, growth factors and literature review

C Perisano, M A Rosa, F Donati, C Barone, G Maccauro

Article ID: 6590
Vol 30, Issue 4S1, 2016
DOI: https://doi.org/10.54517/jbrha6590
Received: 8 January 2017; Accepted: 8 January 2017; Available online: 8 January 2017; Issue release: 8 January 2017

Abstract

The solitary bone cyst is a typical tumor-like lesion of the immature skeleton, whose etio-pathogenesis is still unclear. The purpose of this work is to perform a review of the literature about the different surgical approaches focusing on the role of bone substitutes and growth factors. Literature analysis shows injection techniques of substances such as methylprednisolone, autologous bone marrow, demineralized bone matrix, calcium sulphate and surgical techniques that involve the resection and curettage associated with bone graft and/or intramedullary nailing. Although there are good results currently associated to these techniques and the different ways of treatment, the only evidence-based treatment is given by injections of steroids. However, given the high rate of failure, autologous bone marrow and platelet gel represent a viable therapeutic option.


Keywords

simple bone cyst;unicameral bone cysts;tumor-like lesions;bone tumor


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