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EFFECT OF RESVERATROL ON WNT/β-CATENIN SIGNALLING IN PANCREATIC CANCER CELL LINES
Vol 32, Issue 4S1, 2018
Abstract
Pancreatic cancer is a very aggressive malignant disease due to lack of early diagnosis andchemotherapeutic resistance of the tumor cells. There is distinct evidence that food derived polyphenolspossess chemopreventive effects in the development of several cancers including pancreatic carcinoma.Resveratrol, a phenolic compound found in grape skins and other fruits, is a nutraceutical with severaltherapeutic effects and known anticancer activity. The aim of the study is to analyze the expression ofWnt/ β-catenin signaling pathway genes after treatment with resveratrol.
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Medical Genetics, University of Torino Medical School, Italy
Department of Biomedical, Surgical and Dental Sciences, University of Milan, Italy