VITAMIN D PREVENTS HIGH GLUCOSE-INDUCED ENDOTHELIAL PERMEABILITY

R. SCRIMIERI, L. LOCATELLI, V. ROMEO, E. GIANI, J. MAIER, G.V. ZUCCOTTI, A. CAZZANIGA

Article ID: 6456
Vol 32, Issue 4S1, 2018
DOI: https://doi.org/10.54517/jbrha6456
Received: 8 September 2018; Accepted: 8 September 2018; Available online: 8 September 2018; Issue release: 8 September 2018

Abstract

The endothelium is the gate-keeper of vascular health. Accordingly, endothelial dysfunction is acrucial event in macro-vascular and in small vessel diseases. Since the morbidity and mortality dueto micro- and macro-vascular complications in patients with diabetes is very high, understanding themolecular bases of endothelial dysfunction in response to high glucose is a major issue.



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