Oral Lichen Planus and Epstein-Barr virus: a narrative review

A. Romano, R. Grassi, F. Fiori, G.M. Nardi, R. Borgia, M. Contaldo, R. Serpico, M. Petruzzi

Article ID: 6322
Vol 36, Issue 2S4, 2022
DOI: https://doi.org/10.23812/j.biol.regul.homeost.agents.202236.2S4.11
Received: 9 May 2022; Accepted: 9 May 2022; Available online: 9 May 2022; Issue release: 9 May 2022

Abstract

Oral Lichen planus (LP) is an immune-mediated disease of unknown etiology that affects the oralmucous membranes. Six clinical forms of OLP lesions can be detected individually or associated: papular,reticular, plaque-like, atrophic, erosive, and bullous. The antigen that triggers the inflammatory immunereaction in OLP lesions is yet unclear. The correlation between Epstein-Barr virus (EBV) infections andOral Lichen Planus has been reported in the literature. The present work summarized the evidence toestablish if EBV can play a role in the etiopathogenesis of the disease.



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