Role of Th17 in the pathogenesis of cutaneous inflammatory diseases

A. Chiricozzi; S. Zhang; A. Dattola; M. Gabellini; S. Chimenti; S.P. Nistico

doi:10.54517/jbrha6138

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Role of Th17 in the pathogenesis of cutaneous inflammatory diseases

A. Chiricozzi, S. Zhang, A. Dattola, M. Gabellini, S. Chimenti, S.P. Nistico

Article ID: 6138
Vol 26, Issue 3, 2012

DOI: https://doi.org/10.54517/jbrha6138

Received: 9 October 2012; Accepted: 9 October 2012; Available online: 9 October 2012; Issue release: 9 October 2012

Abstract

Th17 cells are a new T-cell subtype characterized by the capability of producing IL-17. They are reported to be involved in a wide range of cutaneous immune-mediated conditions and, particularly in this review, we sought to elucidate the Th17 role in the pathogenesis of some common inflammatory diseases including psoriasis, allergic contact dermatitis and atopic dermatitis.

Keywords

Th17;IL-17;psoriasis;atopic dermatitis;allergic contact dermatitis

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Medical Genetics, University of Torino Medical School, Italy

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Department of Biomedical, Surgical and Dental Sciences, University of Milan, Italy

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