Ultrasound-guided collagen injections in the treatment of supraspinatus tendinopathy: a case series pilot study

B. Corrado; I. Bonini; V.A. Chirico; E. Filippini; L. Liguori; G. Magliulo; G. Mazzuoccolo; N. Rosano; P. Gisonni

doi:10.54517/jbrha5705

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Ultrasound-guided collagen injections in the treatment of supraspinatus tendinopathy: a case series pilot study

B. Corrado, I. Bonini, V.A. Chirico, E. Filippini, L. Liguori, G. Magliulo, G. Mazzuoccolo, N. Rosano, P. Gisonni

Article ID: 5705
Vol 34, Issue 3S2, 2020

DOI: https://doi.org/10.54517/jbrha5705

Received: 9 July 2020; Accepted: 9 July 2020; Available online: 9 July 2020; Issue release: 9 July 2020

Abstract

Aim of the present pilot study was to verify, for the first time ever, the effects of collagen injections in patients with chronic supraspinatus tendinopathy. Eighteen patients with chronic supraspinatus tendinopathy were treated with a series of 4 type I porcine collagen ultrasound-guided injections, at weekly intervals. The effects were verified at 2-week, 1-month and 3-month follow-up by means of shoulder scoring systems and sonography. A very strong evidence (p< 0.001) of a statistically significant main effect amongst the multiple clinical observation was found. Ultrasound imaging highlighted improvement in the structural integrity of the tendon. Compared to other injection therapies, collagen injections proved to be at least equally effective, faster acting and safer.

Keywords

shoulder impingement syndrome;rotator cuff;supraspinatus;tendinopathy;collagen;injections

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Medical Genetics, University of Torino Medical School, Italy

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Department of Biomedical, Surgical and Dental Sciences, University of Milan, Italy

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2025-02-01

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