Prevention and treatment of peri-prosthetic joint infection using surgical wound irrigation

G. Balato, V.De Matteo, C.De Franco, M. Lenzi, R. Verrazzo, R.de Giovanni, F. Smeraglia, M. Rizzo, T. Ascione

Article ID: 5578
Vol 34, Issue 5S1, 2020
DOI: https://doi.org/10.54517/jbrha5578
Received: 8 November 2020; Accepted: 8 November 2020; Available online: 8 November 2020; Issue release: 8 November 2020

Abstract

Over the past decade, the incidence of revision arthroplasty due to infection has increased substantially, often resulting in multiple surgical interventions with variable success rates and poor clinical outcome. Intraoperative wound irrigation has been proposed to reduce bacterial bioburden and contamination, but currently there is no widely accepted recommendation for the use of topical antiseptics, whether as separate molecules or as a mixed solution. We reviewed studies regarding the use of intraoperative topical antiseptics, their security profile and efficacy in preventing and treating infections of orthopedic implants and introduced a possible combination that may prove valuable in the future


Keywords

wound irrigation;TKA;THA;hydrogen peroxide;povidone iodine;chlorhexidine


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