Probiotics in the add-on treatment of otitis media in clinical practice

M. Gelardi, I. La Mantia, L. Drago, G. Meroni, S.E. Aragona, G. Cupido, C. Vicini, C. Berardi, G. Ciprandi, the Italian Study

Article ID: 5546
Vol 34, Issue 6S1, 2020
DOI: https://doi.org/10.54517/jbrha5546
Received: 8 January 2021; Accepted: 8 January 2021; Available online: 8 January 2021; Issue release: 8 January 2021

Abstract

Otitis media (OM) affects the middle ear and is typically characterized by earache. OM may be classified as acute (AOM) or chronic (COM), based on symptom duration. OM may be clinically suspected, but the diagnosis is usually confirmed by the otoscopy. Antibiotic therapy is frequently used in clinical practice. However, antibiotics often induce intestinal and respiratory dysbiosis associated with some clinical problems. A one-month course of a probiotic mixture (Abincol® containing Lactobacillus plantarum LP01 (1 billion of living cells), Lactobacillus lactis subspecies cremoris LLC02 (800 million living cells), and Lactobacillus delbrueckii LDD01 (200 million living cells), was prescribed in the Group A, and was compared with no addon treatment, such as the Group B. Patients were evaluated at baseline (T0), at the end of antibiotic treatment (T1), at the end of probiotic course (T2), and at the end of 3-month follow-up (T3).


Keywords

otitis media;acute;chronic;antibiotic therapy;dysbiosis;probiotics


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Supporting Agencies



Copyright (c) 2020 M. Gelardi, I. La Mantia, L. Drago, G. Meroni, S.E. Aragona, G. Cupido, C. Vicini, C. Berardi, G. Ciprandi, the Italian Study Group on Upper Respiratory Infections




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