Bleeding control with calcium sulphate after oral surgery in anticoagulant therapy patients

M. Baldoni, D. Lauritano

Article ID: 5505
Vol 33, Issue 6S1, 2019
DOI: https://doi.org/10.54517/jbrha5505
Received: 8 January 2020; Accepted: 8 January 2020; Available online: 8 January 2020; Issue release: 8 January 2020

Abstract

Control of bleeding after oral surgery, is mandatory in patients taking anticoagulants. There are different haemostatic measure to prevent post-surgical bleeding. The aim of our study is to use a homeostatic agent, Calcium sulphate (P30, Ghimas, Bologna, Italy) for controlling post-surgical bleeding in a group of patients treated with warfarin therapy for thromboembolic states. Twenty teeth (12 mandibular molars, 8 maxillary molars) in 20 patients (14 men and 6 woman) with a mean age of 54.3 years (± 10.3 years) were included in the study. The patients were divided in 2 group; in 10 patients of the study group was used Calcium sulphate (P30, Ghimas, Bologna, Italy) in layers to fill the socket after extraction, while in control group was recommended to put a gauze with tranexamic acid in the extraction site immediately after extraction, and half an hour after extraction. The outcome was bleeding in subsequent days. Bleeding at post operative day 1 was significant in 5 patients of control group, otherwise in study group treated with calcium sulfate there was no bleeding in any patient (p. value 0.0055). CaS demonstrated to be a good hemostatic agent for controlling bleeding after oral surgery in patients taking anticoagulants.


Keywords

calcium sulphate;bleeding;haemostasis;warfarin;anticoagulants;thromboembolic states


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