Study of selected therapeutic potentials of Momordica charantia fruit

F Hussain; A Irshad; M Shahid

doi:10.54517/jbrha5219

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Study of selected therapeutic potentials of Momordica charantia fruit

F Hussain, A Irshad, M Shahid

Article ID: 5219
Vol 32, Issue 4, 2018

DOI: https://doi.org/10.54517/jbrha5219

Received: 8 September 2018; Accepted: 8 September 2018; Available online: 8 September 2018; Issue release: 8 September 2018

Abstract

M. charantia extract partitioned in different solvents was assessed for antioxidant (2, 2-diphenyl l-picrylhydrazyl), total phenolic contents (TPC), total flavonoid contents (TFC), antiglycation, alpha amylase and acetylcholinesterase inhibitory activities along with cytotoxic, thrombolytic and antibiofilm potentials. Most effective antioxidant fraction was n-hexane with TPC and TFC, highest in n-butanol and ethanol fractions, respectively. Ethyl acetate fraction showed maximum glycation and alpha amylase inhibitions and optimum acetylcholinesterase inhibition was by ethanol fraction. Fractions exhibited significant hemolytic and thrombolytic efficacies and bacterial growth restraint. The present research reveals some medicinal potency of M. charantia.

Keywords

Momordica charantia;therapeutic properties;2;2-diphenyl l-picrylhydrazyl

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