Factors adversely influencing neurodevelopment

T.C. Theoharides, M. Kavalioti, R. Martinotti

Article ID: 5058
Vol 33, Issue 6, 2019
DOI: https://doi.org/10.23812/19-33n6Edit_Theoharides
Received: 25 September 2019; Accepted: 25 September 2019; Available online: 8 January 2020; Issue release: 8 January 2020

Abstract

Neurodevelopment has been studied extensively, especially in respect to abuse, anoxia, nutritional status and prematurity/low birth weight. However, less attention has been paid to innate and environmental factors, as well as to inflammatory conditions that may adversely affect neurodevelopment and learning in children. These include heavy metals, herbicides and polyvinyl chlorides (PVCs), mycotoxins, viral infections and Lyme disease-associated pathogens, as well as number of conditions such as chronic inflammatory response syndrome (CIRS) and Mast cell activation syndrome (MCAS). Early recognition of factors/conditions that could interfere with neurodevelopment is critical. Corrective actions, including the use of some unique natural flavonoids, could have lasting beneficial results.


Keywords

autism;brain;mast cells;flavonoids;inflammation;learning;neurodevelopment


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Supporting Agencies



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