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Recent recommendations of neonatal septic shock: a review article
Vol 36, Issue 1S1, 2022
Abstract
Septic shock is a complex condition that is potentially fatal if not promptly treated. There are significant differences between clinical presentation in adults and children. In neonates, sepsis and septic shock are characterized by a nonspecific presentation that may delay an early diagnosis, thus contributing to high morbidity and mortality. Management of septic shock in the neonatal intensive care unit (NICU) is based on a multidisciplinary approach which includes prompt recognition of abnormal tissue perfusion and restoration of adequate cardiovascular function through the use of fluids and inotropes, if necessary; eradication of the underlying infection through the early administration of empiric broad-spectrum antibiotics; treatment of organ system dysfunction. This article aims to review current knowledge about the correct treatment and management of septic shock in the neonatal setting
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Medical Genetics, University of Torino Medical School, Italy
Department of Biomedical, Surgical and Dental Sciences, University of Milan, Italy