Link between cutaneous infection, stress and depression

T. Jagmag, M. Tirant, T. Lotti

Article ID: 4400
Vol 31, Issue 4, 2017
DOI: https://doi.org/10.54517/jbrha4400
Received: 6 June 2022; Accepted: 6 June 2022; Available online: 6 June 2022; Issue release: 6 June 2022

Abstract

Depression and mood disorders often develop after dermatological conditions which could be primary or secondary to dermatological pathology. The oxidative and psychological stress cause physiological changes in the body. Shift in the methylation pathway, elevated cortisol, lowered neurotransmitter levels and lowered immune system allow infection to penetrate the body and lead to anxiety and depression. Here, a case report of a 20 year old male patient is presented to show how infectious skin lesions, unresponsive to the usual treatment plan, were treated after using a multipronged approach of addressing systemic infection of Escherichia coli, elevated cortisol levels and nutritional imbalances


Keywords

lymphocutaneous sporotrichosis;oxidative stress;cutaneous infection;depression;phosphatidylserine


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Supporting Agencies



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