CLINICAL EFFECT OF MECHANICAL FRAGMENTATION COMBINED WITH RECOMBINANT TISSUE PLASMINOGEN ACTIVATOR ARTERY THROMBOLYSIS ON ACUTE CEREBRAL INFARCTION

XF. JIA, Z. HONG, JH. FAN, YM. ZHANG

Article ID: 4213
Vol 30, Issue 3, 2016
DOI: https://doi.org/10.54517/jbrha4213
Received: 6 June 2022; Accepted: 6 June 2022; Available online: 6 June 2022; Issue release: 6 June 2022

Abstract

This study aims to explore the clinical effect of mechanical fragmentation combined with recombinant tissue plasminogen activator (rt-PA) artery thrombolysis on acute cerebral infarction (ACI). One hundred and thirty-two cases of ACI patients were randomly divided into an experimental group (66 patients) and a control group (66 patients). The experimental group was treated with mechanical fragmentation combined with rt-PA artery thrombolysis method, while the control group was treated with only the rt- PA artery thrombolysis method. All the patients had their basic information recorded. A computational analysis on National Institutes of Health Stroke Scale (NIHSS) scores, curative effect and bleeding data was carried out. The results showed that in the experimental group the curative effects were better and there were fewer complications. Accordingly, we conclude that mechanical fragmentation combined with rt-PA artery thrombolytic method is a safe and reliable therapy with significant curative effects. It improves the NIHSS scores of the patients markedly and reduces the incidence of subsequent pneumonia.


Keywords

acute cerebral infarction;artery thrombolysis;clinical effect;mechanical fragmentation


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