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Comparison of different thromboembolism risk scores with the predictive value of left atrial thrombosis and/or spontaneous ultrasound in patients with non-valvular atrial fibrillation
Vol 2, Issue 2, 2021
Issue release: 31 December 2021
VIEWS - 3630 (Abstract)
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Abstract
Objective: To compare the predictive value of CHADS2, CHA2DS2-VASc, ATRIA and R2-CHADS2 scores and left atrial thrombosis and/or spontaneous ultrasound in patients with non-valvular atrial fibrillation (AF) Methods patients with non-valvular atrial fibrillation who were hospitalized in the Department of Cardiology of Sun Yat Sen Memorial. Results: 564 patients were included. The age of patients was (61.1 ± 10.1) years old, of which 63.3% were men. Hypertension was the most common complication, which was found in 49.6% of patients. Patients were divided into thrombus group (n = 82) and non-thrombus group (n = 482) according to the presence of left atrial thrombus and/or spontaneous ultrasound development CHADS2 score in thrombotic group (1[0,2]) was higher than that in non-thrombotic group (1[0,1]) (P < 0.05), and CHA2DS2-VASc score in thrombotic group (2[1,3]) was higher than that in non-thrombotic group (2[1,2]) (P < 0.05) 11.06%, 13.39%, 26.58%, 18.52% and 16.67% of patients with CHADS2 score of 0, 1, 2, 3 and 4 had left atrial thrombus and/or spontaneous ultrasound (P fortrend = 0.016), and 11.06%, 13.39% and 23.68% of patients with low, medium and high risk had left atrial thrombus and/or spontaneous ultrasound (P fortrend = 0.004); 10.81%, 10.19%, 16.57%, 21.05%, 21.05%, 16.67%, 14.29% of patients with CHA2DS2-VASc score of 0, 1, 2, 3, 4, 5, 6 or above had left atrial thrombosis and/or spontaneous ultrasound development (P fortrend = 0.019), and 8.75%, 13.90% and 19.35% of patients with low, medium and high risk had left atrial thrombosis and/or spontaneous ultrasound development (P fortrend = 0.004); The area under the ROC curve of ATRIA score and R2-CHADS2 score was 0.562. The samples based on this study had no statistical significance in the diagnosis of left atrial thrombosis and/or spontaneous ultrasound (P>0.05). Conclusion: CHADS2 score and CHA2DS2-VASc score have considerable and limited diagnostic value for left atrial thrombosis and/or spontaneous ultrasound in patients with non-valvular atrial fibrillation.
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Prof. Prakash Deedwania
University of California,
San Francisco, United States
