Advances in the Application of Chromatographic Techniques in Forensic Toxicology Fund

Shan Li, Xiaoyi Wang, Yanan Zhang, Zishen Wan, Yuanfeng Wang

Article ID: 1998
Vol 4, Issue 2, 2023

VIEWS - 104 (Abstract)

Abstract

With the gradual advancement of knowledge and civilization, forensic science and technology is steadily developing and evolving. Chromatography, as an important analytical technique with the advantages of simplicity, rapidity and high sensitivity, has been widely used by researchers in various countries in the process of detecting toxic substances and drugs in forensic science. This paper presents a comprehensive analysis and exploration of chromatographic techniques from three perspectives: the development of chromatography, its classification according to the two-phase state, chromatographic separation mechanism and the nature of the stationary phase, and the applications of chromatographic techniques. The future development trend of chromatographic analysis technology is also prospected in order to provide new ideas for the development and research2o2f other technologies in thefield of forensic science.


Keywords

Forensic science; chromatography; thin layer chromatography; gas chromatography; liquid chromatography

Full Text:

PDF



References

1. Campelo EL, Caldas ED.Postmortem data related to drug and toxic substance use in the Federal District, Brazil, from 2006 to 2008[J]. Forensic Sci Int, 2010, 200(1-3):136-140.

2. Below E, Lignitz E.Cases of fatal poisoning in post- mortem examinations at the Institute of Forensic Medicine in Greifswald--analysis offive decades of post-mortems[J]. Forensic Sci Int, 2003, 133(1-2):125-131.

3. Seymour A, Black M, Oliver JS. Drug related deaths in the Strathclyde region of Scotland, 1995-1998[J]. Forensic Sci Int, 2001, 122(1):52-59.

4. Soltaninejad KM, Faryadi, Sardari F.Acute pesticide poisoning related deaths in Tehran during the period 2003- 2004[J]. J Forensic Leg Med, 2007, 14(6):352-354.

5. China's national drug control office, report on China's drug control situation in 2020 [r], June 2021

6. Hadidi KA, Almasad JK, Al-Nsour T, et al.Determination of tramadol in hair using solid phase extraction and GC-MS[J]. Forensic Sci Int, 2003, 135(2):129-136.

7. Ju Yanyan, Yang chongjun, Liu Bingjie, etc. Detection of 17 drugs in drug driving cases by ultra high performance liquid chromatography tandem mass spectrometry [J]. Criminal technology, 2020, 45 (5):495-498

8. Hesse G, Weil H, et al.Miehael Tswett’s First Paper on Chromatography[M]. Isis, 1956.

9. Palmer LS. Carotenoids and Related Pigments:The Chromolipids. Am Chem Soc Monogr[M]. Ser Chemical Calalog Co.New York, 1922.

10. Jandera P, Churacek J.Gradient Elution in Liquid Chromatography[M]. Theory and Practice, Epsevier Science Publishers, B.V., 1985.

11. Sentell KB, Dorsey JG. Retention mechanisms in reversedphase liquid chromatography. Stationary-phase bonding density and partitioning[J]. Anal Chem, 1989, 61(9):930-934.

12. Wang Hongfei, Zhou Yahong Study on the method of rapid drug detection in drug driving scene [J]. Progress in analytical chemistry, 2018, 8 (2):65-73

13. Wei Liqing Qualitative and quantitative analysis of heroin by TLC scanning [C]. Chinese society of forensic medicine Proceedings of the first national drug testing technology exchange, 1997:315-317

14. Chen xueguo, Wang Xinling, Da Hui, etc Research progress of planning drug mdpv [J]. Shandong chemical industry, 2014, 43 (4):60-61, 65

15. Cheng Xinzhi, Huang Linxing Application of thin layer chromatography in drug detection [J]. Guangdong Public Security Science and technology, 1997, 4 (7):25-28

16. Zhou Lianzhen Application of thin layer chromatography in drug detection [J]. Journal of Youjiang Medical College for nationalities, 2000, 22 (6):949

17. Sabino BD, R omao W, Sodré ML, et al.Analysis of cocaine and crack cocaine via thin layer chromatography coupled to easy ambient sonic-spray ionization mass spectrometry[J]. Am J Anal Chem, 2011, 2:658-664.

18. De Carvalho TC, Tosato F, Souza LM, et al.Thin layer chromatography coupled to paper spray ionization mass spectrometry for cocaine and its adulterants analysis[J]. Forensic Sci Int, 2016, 262:56-65.

19. Niu Yong, Lu yanxu, Liu Yuan Review on the testing methods of cannabis drugs [J]. Criminal technology, 2004, 6:21-23

20. Zhang Xiao, Zhang Xiaofei, Li Haixia, et al Establishment of gas chromatographic detection method for poisons and drugs in human blood [J]. Journal of Changchun University of science and Technology (NATURAL SCIENCE EDITION), 2014, 37 (1):153-155159

21. Ni Siyang, Wu Feng, Wang Shumin, et al Study on the detection of hair samples of drug addicts with different degrees of addiction by gas chromatography-mass spectrometry [J]. Chinese Journal of clinical pharmacology, 2020, 36 (16):2497-2500

22. Shi Jiawei, Zhou Jingfeng, Zhao Yonggang Analysis of four amphetamine drugs in urine by pipette solid phase microextraction gas chromatography triple quadrupole mass spectrometry [J]. Chinese Journal of drug abuse, 2020, 29 (2):111-116141

23. pan Lu, Luo Shiyong Determination of four organochlorine pesticides by quechers gas chromatography [J]. Guangdong chemical industry, 2021, 48 (8):269-270289

24. Lee JG, Lee CG, Kwag JJ, et al.Fast analysis of nicotine in tobacco using double-shot pyrolysis--gas chromatographymass spectrometry[J]. J Agric Food Chem, 2007, 55(4):1097-102.

25. Jiang Limin, Chen xueguo, Zhang haopei, et al Analysis of six synthetic cannabinoids in hair by liquid chromatography electrospray spray ion trap mass spectrometry [J]. Analytical testing technology and instruments, 2020, 26 (3):169-178

26. forest width Detection of three common synthetic cannabinoids in body fluids by ultra high performance liquid chromatography tandem mass spectrometry [D] Beijing: People's Public Security University of China, 2018

27. Chang Ying, Xu Peng, Gao Lisheng Determination of methcathinone by liquid chromatography [J]. Chemical analysis and metrology, 2012, 21 (1):67-69

28. Zhong Jianjun, sun Huihui Research progress in the analysis and detection of amphetamines in biological samples [J]. Chemical engineer, 2016, 30 (6):48-51

29. Xia Jiuzhi Analysis of methamphetamine content in suspected drugs by gas chromatography [J]. Professional windows, 2021 (12):31

30. Yu Lei, he Pengxiang, Liu Jin, etc Gc/ms analysis of main active components in "katong" [J]. Chinese Journal of drug abuse, 2020, 26 (1):1-3

31. Qian Zhenhua, Chen yuemeng, Hua Zhendong Study on qualitative test method of fentanyl like substance carfentanil [J]. Analysis laboratory, 2019, 38 (3):270-274

32. He Tianyu, Hu Shenghua Test and analysis of flutamidone by gas chromatography-mass spectrometry [J]. Journal of Wuhan public security cadre college, 2021 (1):48-52

33. Meng Pinjia, Wang Yanyan, Wang Jifen, et al Analysis of morphine drugs in blood by silylation gas chromatography-mass spectrometry [J]. Analysis laboratory, 2009, 28 (10):13-16

34. Peng Shanshan, Wang Jifen, Xin Guobin Study on the determination method of qualitative analysis results of six common drugs in urine under GC-MS selective ion mode [J]. Chemical research and application, 2020, 32 (2):214-220

35. Pragst F, Balikova MA. State of the art in hair analysis for detection of drug and alcohol abuse[J]. Clin Chim Acta, 2006, 370(1-2):17-49.

36. Cooper GA, Kronstrand R, Kintz P.Society of Hair Testing guidelines for drug testing in hair[J]. Forensic Sci Int, 2012, 218(1-3):20-24.

37. Meng Pinjia Comparison of hair characteristics analysis between heroin and methamphetamine drug abusers [J]. Applied chemistry, 2014, 31 (1):103-108

38. Gicquel T, Richeval C, Mesli V, et al.Fatal intoxication related to two new arylcyclohexylamine derivatives (2F-DCK and 3-meo-PCE)[J]. Forensic Sci Int, 2021, 324 :110852.


DOI: https://doi.org/10.54517/aas.v4i2.1998
(104 Abstract Views, 0 PDF Downloads)

Refbacks

  • There are currently no refbacks.