Efficacy and safety of minimally invasive percutaneous nephrolithotomy(MPCNL) and standard channel percutaneous nephrolithotomy(SPCNL) in the treatment of kidney stones:A meta analysis

Abstract

Objective: To evaluate the efficacy and safety of minimally invasive percutaneous nephrolithotomy(MPCNL) standard channel percutaneous nephrolithotomy(SPCNL) in the treatment of kidney stones. Methods: We searched pubmed, Cochrane Liabrary, CNKI, VIP , Wangfang database from January 1, 1992 to April 1, 2015. Screening of the two methods of treatment of kidney stones randomized controlled trials (RCT) and quality assessment, using revman5.2 software for statistical analysis. Results: A total of nine RCT, 1017 patients, 508 cases in MPCNL group, 509 cases in SPCNL group. The results show: the stones clearance , MPCNL group was lower than SPCNL group [OR=0.62, 95%CI(0.43, 0.91), P=0.01]; in terms of operative time, MPCNL group was longer than SPCNL group [MD = 14.23 , 95% CI (6.30, 22.16), P = 0.0004]; hospitalization time, blood loss, total complications, were no significant difference between the two group, the results are [MD = 0.88, 95% CI (-0.69 , 2.44), P = 0.27], [MD =-19.87, 95% CI (-64.36, 24.61), P = 0.38], [OR=1.28, 95%CI(0.90, 1.84), P=0.17]. Conclusion: the stone clearance rate:MPCNL group was lower than SPCNL group, the operative time of MPCNL group was longer which may affect postoperative recovery, the complications, hospital stay, blood loss, the two groups had no significant difference. So , we tend to standard channel percutaneous nephrolithotomy in the treatment of common type of kidney stones.