Asia Pacific Academy of Science Pte. Ltd. (APACSCI) specializes in international journal publishing. APACSCI adopts the open access publishing model and provides an important communication bridge for academic groups whose interest fields include engineering, technology, medicine, computer, mathematics, agriculture and forestry, and environment.
Nephrotic syndrome in pediatrics
Vol 1, Issue 1, 2020
Download PDF
Abstract
Nephrotic syndrome is a glomerulopathy caused by renal diseases that increase the permeability of the glomerular filtration barrier; minimal change disease is the cause most associated with the development of nephrotic syndrome in pediatrics. The clinical manifestations that characterize this syndrome are: proteinuria in nephrotic range, hypoalbuminemia, edema in areas of decline and alterations in the lipid profile. The diagnosis is made by clinical findings and other studies including urinalysis, urinary proteins as initial tests, serum albumin levels and sometimes alterations in the lipid profile, in few cases renal biopsy is required to confirm the diagnosis. Most patients respond to first line medical treatment with disease remission and symptomatology control.
Keywords
References
1. Román E. Pediatric nephrotic syndrome. Spanish Association of Pediatrics [Internet]. 2014 [cited 20 November 2019];1:283-301. Available from: http://www.aeped.es/protocolos/
2. Niaudet P. Etiology, clinical manifestations, and diagnosis of nephrotic syndrome in children. UpToDate [Internet]. 2019 [cited 20 November 2019];. Available from: https://www.uptodate.com/contents/etiology- clinical-manifestations-and-diagnosis-of-nephrotic-syndrome-in-children/print?search=sindrome
3. MALDONADO E, REYNA J. NEPHROTIC SYNDROME IN THE OLDER INFANT. ACADEMIC UNIT OF CHEMICAL AND HEALTH SCIENCES [Internet]. 2018 [cited 15 December 2019];. Available from: http://repositorio.utmachala.edu.ec/handle/48000/12312
4. Ramos P, Villeda C. Minimal change nephrotic syndrome: Current events. Department of Pediatrics, Hospital San José Tec de Monterrey [Internet]. 2018 [cited 15 December 2019];:29-32. Available from: http://www.hsj.com.mx/media/29003/rev 06 s ndrome nefr tico de cambios m nimos - actualidad.pdf.
5. Kliegman R, Stanton B, St. Geme J, Schor N. Nelson treatise on pediatrics. 20th ed. Barcelona, Spain: Elsevier Spain; 2016.
6. % Restrepo C. RENAL ANATOMY AND PHYSIOLOGY. Basic Nephrology 2 [Internet]. 2018 [cited 15 December 2019];:1-9. Available from: http://asocolnef.com>wp-content>uploads>2018/03 > Cap01.
7. Cisneros L. Nephrotic syndrome in children: role of the pediatrician and pediatric nephrologist. Journal of the Faculty of Human Medicine [Internet]. 2018 [cited 25 November 2019];1:55-64. Available from: http://revistas.urp.edu.pe/index.php/RFMH
8. Fernández S, Vozmediano C, Rivera F. Clinical syndromes in nephrology. Revista nefrologia [Internet]. 2019 [cited 25 November 2019];. Available from: http://www.revistanefrologia.com/
9. Nephrotic syndrome in children. Médecins Sans Frontières Clinical and therapeutic guide [Internet]. 2019 [cited 15 December 2019];. Available from: https://medicalguidelines.msf.org/viewport/CG/latest/sindrome- nephrotic-in-the-child-23443428.html.
10. Arcos C. NEPHROTIC SYNDROME. Basic Nephrology 2 [Internet]. 2018 [cited 15 December 2019];:69-77. Available from: http://asocolnef.com/formacion-2/formacion/libro-nefrologia-basica-2/
11. Gómez A, Pérez L, Chaviano O. Nephrotic syndrome in pediatrics: an impact in childhood. Revista Finlay (online journal) [Internet]. 2019 [cited 25 November 2019];9(1):20-25. Available from: http://www.revfinlay.sld.cu/index.php/finlay/article/view/683
12. diagnosis and treatment of primary nephrotic syndrome in children. Mexican Institute of Social Security, coordination of high specialty medical units [Internet]. 2013 [cited 15 December 2019];. Available from: http://www.cenetec.salud.gob.mx > imss_271_13_sxnefroticoprimarioen_ninosger
13. Niaudet P. Complications of nephrotic syndrome in children. UpToDate [Internet]. 2019 [cited 25 November 2019];. Available from: https://www.uptodate.com/contents/complications-of-nephrotic-syndrome-in-children/print?search=sindrome
14. Cadnapaphornchai MA, Tkachenko O, Shchekochikhin D, Schrier RW. The nephrotic syndrome: pathogenesis and treatment of edema formation and secondary complications. Pediatric Nephrology. 2013 08 30;29(7):1159-1167. https://doi.org/10.1007/s00467-013-2567-8
15. Niaudet P. Symptomatic management of nephrotic syndrome in children. UpToDate [Internet]. 2019 [cited 25 November 2019];. Available from: https://www.uptodate.com/contents/symptomatic-management-of- nephrotic-syndrome-in-children/print?search=sindrome
16. Meyrier A, Niaudet P. Acute kidney injury complicating nephrotic syndrome of minimal change disease. Kidney International. 2018 Nov;94(5):861-869. https://doi.org/10.1016/j.kint.2018.04.024
17. Niaudet P. Glomerular disease: Evaluation in children. UpToDate [Internet]. 2019 [cited 25 November 2019];. Available from: https://www.uptodate.com/contents/glomerular-disease-evaluation-in-children/print?search=sindrome
18. Gillion O. Evaluation of proteinuria in children. UpToDate [Internet]. 2019 [cited 25 November 2019];. Available from: https://www.uptodate.com/contents/evaluation-of-proteinuria-in-children/print?search=
19. Arcos C. NEPHROTIC SYNDROME. Basic Nephrology 2 [Internet]. 2018 [cited 15 December 2019];:69-77. Available from: http://asocolnef.com/formacion-2/formacion/libro-nefrologia-basica-2/
20. Consensus on the treatment of nephrotic syndrome in childhood. Archivos Argentinos de Pediatria. 2014 06 01; 112(3). https://doi.org/10.5546/aap.2014.277
21. Niaudet P, Meyrier A. Idiopathic nephrotic syndrome (Turner N, ed). Oxford University Press; 2018 05. https://doi.org/10.1093/med/9780199592548.003.0054 update001
22. Velásquez Jones L. Treatment of idiopathic nephrotic syndrome in children. Medical Bulletin of the Children's Hospital of Mexico. 2014 09;71(5):315-322. https://doi.org/10.1016/j.bmhimx.2014.07.002
23. Lombel RM, Gipson DS, Hodson EM. Treatment of steroid-sensitive nephrotic syndrome: new guidelines from KDIGO. Pediatric Nephrology. 2012 Oct 03;28(3):415-426. https://doi.org/10.1007/s00467-012-2310- x
24. Niaudet P, Gillion O. Steroid-resistant idiopathic nephrotic syndrome in children: Management. UpToDate [Internet]. 2019 [cited 9 December 2019];. Available from: https://www.uptodate.com/contents/steroid- resistant-idiopathic-nephrotic-syndrome-in-children-management/print?search=sindrome
25. Palma F. Nephrotic syndrome in patients aged 1 to 12 years admitted to the pediatric unit of the Verdi Cevallos Balda Hospital. Revista cientifica DOMINIO DE LAS CIENCIAS [Internet]. 2016 [cited 25 November 2019];2:120-131. Available from: http://dominiodelasciencias.com/ojs/index.php/es/index
Refbacks
- There are currently no refbacks.
Copyright (c) 2020 Abarca Zúñiga Vivian, Álvarez Rodríguez Nicole
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
This site is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
.png)
Prof. Wei-Yen Hsu
National Chung Cheng University, Taiwan
