Nephrotic syndrome in pediatrics

Abstract

Nephrotic syndrome is a glomerulopathy caused by renal diseases that increase the permeability of the glomerular filtration barrier; minimal change disease is the cause most associated with the development of nephrotic syndrome in pediatrics. The clinical manifestations that characterize this syndrome are: proteinuria in nephrotic range, hypoalbuminemia, edema in areas of decline and alterations in the lipid profile. The diagnosis is made by clinical findings and other studies including urinalysis, urinary proteins as initial tests, serum albumin levels and sometimes alterations in the lipid profile, in few cases renal biopsy is required to confirm the diagnosis. Most patients respond to first line medical treatment with disease remission and symptomatology control.