Prof. Marcello Iriti
Special Issue Information
Dear Colleagues,
This Special Issue on "Emerging Trends in Plant-Derived Immune Regulators: Biosynthesis, Bioactivity, and Translational Medicine" aims to highlight cutting-edge advancements in the discovery, characterization, and therapeutic application of plant-derived compounds that modulate immune responses. Plants have long been a treasure trove of bioactive molecules with immunomodulatory properties, offering novel pathways for addressing autoimmune disorders, infectious diseases, and cancer. This issue will focus on the interplay between biosynthesis mechanisms, bioactivity validation, and clinical translation of these natural immune regulators.
We invite submissions that explore the following themes (but are not limited to):
1. Biosynthesis Pathways: Metabolic engineering, synthetic biology, and omics approaches to enhance or elucidate the production of plant-derived immune-active compounds.
2. Bioactivity Mechanisms: In vitro and in vivo studies on immune modulation, including interactions with innate/adaptive immunity, cytokine networks, and immune cell signaling.
3. Translational Medicine: Preclinical and clinical trials of plant-based immunotherapeutics, formulation strategies, and pharmacokinetic/pharmacodynamic analyses.
4. Biotechnological Innovations: CRISPR-based editing, plant cell cultures, and bioreactor systems for scalable production of immune regulators.
5. Cross-Disciplinary Synergies: Integration of ethnopharmacology, computational biology, and AI-driven drug discovery to accelerate plant-based immune modulator development.
Contributions may include original research articles, comprehensive reviews, methodological advances, or case studies that address challenges in efficacy, safety, and regulatory compliance. This Special Issue seeks to bridge the gap between traditional knowledge and modern biomedical research, fostering collaboration among botanists, pharmacologists, immunologists, and biotechnologists.
Prof. Marcello Iriti
Guest Editor
Keywords
Plant-Derived Immune Modulators
Biosynthesis and Bioactivity
Translational Immunology
Ethnopharmacological Studies
Nutritional Immunology
Microbiota-Immune Interactions
Natural Products, Pharmacognosy
Omics Technologies
Clinical Applications
Exercise Immunology/Sport & Immunity
Osteoimmunology/Bone & Immune System