Dear colleagues,

The integration of nanotechnology with biology and medicine is driving a new era of advanced therapeutic solutions. The special issue, "Bridging Nanotechnology, Biology, and Medicine for Next-Generation Therapeutics," focuses on recent innovations where nanoscale technologies meet biological systems to create highly targeted, efficient, and personalized treatments. Nanotechnology and advanced drug delivery systems play a vital role in regulating the human body by enabling targeted, controlled, and sustained release of therapeutic agents. These technologies improve drug bioavailability, reduce side effects, and enhance treatment efficacy by delivering drugs directly to specific tissues or cells. Nanotechnology and drug delivery systems aid in regulating the human body by precisely targeting and modulating physiological processes. Nanoscale carriers can deliver drugs in response to specific stimuli—like pH, temperature, or enzymes—ensuring timely intervention in imbalances such as inflammation, hormone levels, or glucose regulation. These smart systems enhance therapeutic precision, support controlled release, and reduce systemic toxicity. By interacting with cellular mechanisms, they help restore or maintain homeostasis, correct dysfunctional pathways, and adapt treatment to the body’s needs in real time. Such innovations are transforming disease management, especially in chronic conditions like cancer, diabetes, and neurological disorders. Moreover, they support real-time monitoring and on-demand drug release, contributing to personalized therapy and effective disease management. When combined with an in-depth understanding of biological processes and clinical needs, these technologies can significantly enhance therapeutic outcomes and patient care.

This issue welcomes original research and critical reviews on topics such as novel nanomaterials, bio-inspired delivery systems, smart nanoparticles for diagnostics, nanotechnology-driven immunotherapies, and regenerative medicine approaches. It also encourages discussion around the practical challenges of translating laboratory findings into clinical therapies, including regulatory hurdles and safety assessments. By bringing together experts from diverse fields, the issue aims to foster multidisciplinary collaborations that are essential for the development of future therapeutics. The ultimate goal is to highlight how nanotechnology, when thoughtfully integrated with biological sciences and medical practice, can lead to safer, smarter, and more effective healthcare solutions. 

• Nanomedicine 

• Targeted Drug Delivery 

• Nanocarriers 

• Biomimetic Nanotechnology 

• Regenerative Medicine 

• Theranostics 

• Translational