Dear colleagues,

In recent years, the rapid advancement of nanotechnology has led to the development of a wide array of chemical compounds that are increasingly utilized in various industries, including electronics, medicine, and cosmetics. Concurrently, the extensive use of pesticides in agriculture has raised significant concerns regarding their neurotoxic effects, particularly when these substances persist in natural products such as fruits and food. This Special Issue aims to address the urgent need for comprehensive research on the neurotoxicological impacts of newly developed chemical substances, particularly nanomaterials and pesticides, and their role in endocrine disruption. 

The issue will explore the latest findings on how these chemicals interact with the nervous system and endocrine pathways, leading to various health implications, including hormonal imbalances, neurodevelopmental disorders, and other neurological conditions. We will emphasize the importance of interdisciplinary approaches in understanding these complex interactions, as well as the need for collaborative efforts among researchers, healthcare professionals, and policymakers to mitigate risks associated with exposure to these substances, particularly through dietary intake. 

We invite contributions that cover a broad range of topics, including but not limited to: 

- Molecular and cellular mechanisms of neurotoxicity associated with nanomaterials and pesticides 

- The role of endocrine disruptors in neurological health and development 

- Persistence and bioaccumulation of pesticides in food products and their potential health risks 

- Epidemiological studies linking chemical exposure to neurodevelopmental outcomes 

- Novel in vitro and in vivo models for studying neurotoxicity of emerging compounds 

- Innovative methodologies for assessing the neurotoxic effects of emerging chemical compounds and pesticides 

- Transgenerational effects of neurotoxic chemical exposure 

- Blood-brain barrier permeability to nanomaterials and implications for neurotoxicity 

- Regulatory challenges and public health implications of findings in this field 

- Mitigation strategies and safer alternatives to neurotoxic compounds 

This Special Issue comes at a critical time when there is growing global concern about the impact of manufactured chemicals on human health. With the increasing prevalence of neurological and developmental disorders, there is an urgent need to better understand the role that nanomaterials, pesticides, and endocrine disruptors may play in these conditions. By bringing together cutting-edge research in this field, we aim to facilitate the development of more effective preventive and regulatory strategies to protect human health and the environment. 

We welcome a diversity of articles, such as conceptual and empirical articles, reviews, critical comments, and meta-analyses, for submission to this Special Issue. We will accept manuscripts from different disciplines, addressing topics related to the scope. 

- Neurotoxicity 

- Nanomaterials 

- Pesticides 

- Endocrine disruption 

- Hormonal imbalances 

- Neurodevelopmental disorders 

- Food safety