Prof. Giuseppe Minervini
Special Issue Information
Dear colleagues:
The oral microbiota is home to more than 700 species of bacteria, fungi, viruses, and archaea. These microorganisms maintain the homeostasis of the oral environment through sophisticated metabolic collaboration and signal communication. They not only participate in food digestion, but also resist the invasion of pathogens by producing antibacterial substances, while forming a dynamic balance with the host immune system. Oral microbiome disorders are also potentially associated with systemic diseases such as diabetes and cardiovascular diseases, and their complex role in health and disease is becoming a multidisciplinary research hotspot.
Dentistry is a constantly evolving discipline that benefits from ongoing advancements in clinical techniques, biomedical research, and technological innovation. The integration of biological sciences—such as molecular biology, genetics, immunology, and tissue engineering—is transforming our understanding of oral health and disease. These insights are paving the way for more personalized, regenerative, and minimally invasive dental therapies.
At the same time, regulatory frameworks and evidence-based clinical guidelines continue to shape the standards of care and ensure the safety and efficacy of dental interventions. The development of new materials, digital workflows, and biologically-driven approaches is guided not only by innovation but also by compliance with ethical and legislative principles.
This Special Issue aims to gather high-quality contributions from all areas of dental science and practice. Topics of interest include, but are not limited to: oral homeostatic regulation, periodontology, prosthodontics, oral pathology, oral and maxillofacial surgery, orthodontics, Obstructive sleep apnea syndrome, digital dentistry, biologically-based therapies, biomaterials, and regulatory perspectives in dental research and practice.
We welcome submissions of original research articles, reviews, and clinical studies that provide novel insights or contribute to the advancement of modern, safe, and biologically-informed dental care.
Keywords
Oral Microbiota
Dental Microenvironment
Oral Homeostatic Regulation
Orofacial Pain
Temporomandibular Disorders
Dentistry
Obstructive Sleep Apnea Syndrome（Osas)
Oral Surgery